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In a further embodiment, the tetracycline compounds of the invention are used to treat such disorders as described in US. In certain embodiments, a straight chain or branched chain alkenyl group has 6 or fewer carbon atoms in its backbone (eg, C 2-C 6 for straight chain, C 3-C 6 for branched chain). Examples of substituents include those which allow the compound to perform its intended function?

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